Research.

The Academic Unit of Radiology at the University of Sheffield performs the majority of its research using Magnetic Resonance techniques. 

Our particular areas of interest are neuro imaging, fetal imaging and the use of hyperpolarised agents for MR.

The MR Unit opened in 1991 followed by the creation of the Academic Unit of Radiology in 1996 after the appointment of Professor Paul Griffiths as head of unit. The unit has grown in size and now consists of seven senior academics based in either Radiology or Medical Physics.

We currently operate four MR scanners at different sites across Sheffield; two based at the Royal Hallamshire Hospital (1.5T and 3T), Sheffield Children's Hospital (1.5T) and a small bore 0.2T system based at the Jessop Wing of the Royal Hallamshire Hospital. 

The Academic Unit of Radiology has research partnerships with two major MR manufacturers (Philips Medical Systems and General Electric Health Care).

Faculty

Dr Amaka Offiah - HEFCE clinical senior lecturer is also an honorary consutant radiologist at Sheffield Children's Hospital with an interest in the musculoskeletal system in general and child abuse and skeletal dysplasias in particular. She is a member of the Academic Unit of Child Heath and Mellanby Centre for Bone Research. Further details are available at:

http://mellanbycentre.dept.shef.ac.uk/default.htm

http://www.shef.ac.uk/humanmetabolism/people/offiah

Dr Elspeth Whitby - is a clinical senior lecturer in radiology based in the Academic department of reproductive and developmental medicine and a honorary consultant radiologist at Sheffield teaching hospitals. Her main interest is in obstetric imaging including both the fetus and the placenta. She collaborates with academic radiologists in child health and with a wide range of clinicians. She lectures and examines on the medical school course and supports research students at all levels of medical training. Further details are available on the University of Sheffield Website.

http://www.shef.ac.uk/humanmetabolism/people/whitb

For further information please see the Sheffield University website.

2017

1. Multiple Sclerosis Update: use of MRI for early diagnosis, disease monitoring and assessment of treated related complications. Igra MS, Paling D, Wattjes MP, Connolly DJ, Hoggard N.Br J Radiol. 2017 Mar 31
2. Paddock M, Akram R, Jarvis DA, Armitage P, Song S, Madhuvrata P, Griffiths PD. The assessment of fetal brain growth in diabetic pregnancy using in utero magnetic resonance imaging. Clinical Radiology. 2017;72(5);427.e1-427.e8.
3. Paddock M, Sprigg A, Offiah AC. Re: Imaging and reporting considerations for suspected physical abuse (non-accidental injury) in infants and young children. Part 1: initial considerations and appendicular skeleton. A reply. Clinical Radiology 2017;72(5):422
4. Paddock M, Sprigg A, Offiah AC. Imaging and reporting considerations for suspected pgysical abuse (non-accidental injury)in infants and young children. Part 2 Axial skeleton and differential diagnosis. Clinical Radiology. 2017;72(3):189-201.
5. Paddock M, Sprigg A, Offiah AC. Imaging and reporting considerations for suspected physical abuse (non-accidental injury) in infants and young children. Part 1: Initial considerations and appendicular skeleton. Clinical Radiology. 2017;72(3):179-188.
6. Paddock M, Hodgson T, Bhattacharyya D. Bilateral incudomalleolar dislocations: an unusual cause of deafness. BMJ Case Reports 2017;doi:10.1136/bcr-2016-2018733
7. A qualitative comparison of arterial spin labelling and dynamic susceptibility contrast MRI in 52 children with a range of neurological conditions. Armitage P, Skipper N, Connolly DJA, Griffiths PD. The British Journal of Radiology 2017.
8. T.Adlan, Y.Shahin, P.Kember, J.Isaacs, R.Seymour ‘Retrospective cohort study on Angio-Seal closure device safety and effectiveness in antegrade superficial femoral artery punctures: a comparison with antegrade common femoral artery punctures’. International Journal of Surgery 2017; 48:225-27.
9. Y.Shahin. ‘Re: Intraprocedural distal embolization after femoropopliteal angioplasty: is there a role for below-the-knee stents? a statistical analysis point of view’. In press. Cardiovascular and Interventional Radiology Journal 2017.

2016

1. Jarvis DA, Akram R, Mandefield L, Paddock M, Armitage P, Griffiths PD. Quantification of total fetal brain volume using 3D MR imaging data acquired in utero. Prenatal Diagnosis. 2016;36(13):1225-1232.
2. Sutton AJ,Vohra RS, Hollyman M, Marriott PJ, Buja A, Alderson D, Pasquali S, Griffiths EA, CholeS Study Group and the West Midlands Research Collaborative. ‘Cost-effectiveness of emergency versus delayed laparoscopic cholecystectomy for acute gallbladder pathology’. In press. British Journal of Surgery 2016.
3. CholeS Study Group,West Midlands Research Collaborative. ‘Population-based cohort study of variation in the use of emergency cholecystectomy for benign gallbladder diseases’. In press. British Journal of Surgery 2016.
4. CholeS Study Group,West Midlands Research Collaborative. ‘Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases’. In press. British Journal of Surgery 2016.
5. F.A.Mazari,Y.Shahin, J.A.Khan, N.Samuel, D.Carradice, P.T.McCollum, I.C.Chetter ‘Comparison of use of Short Form-36 domain scores and patient responses for derivation of preference-based SF6D index to calculate quality adjusted life years (QALYs) in patients with intermittent claudication’. In press. Annals of Vascular Surgery 2016.

2015

1. Paddock M. Lines on a posteroanterior chest radiograph. British Medical Journal. 2015;350:h1437.
2. Comparison of clinically suspected injuries detected at whole-body CT in suspected multi-trauma victims. Shannon L, Peachey T, Skipper NT,Adiotomre E,Chopra A, Marappan B, Kotnis N. Clinical Radiology 2015.

2014

1. Paddock M, Demetriou A, Nicholl R. Are we considering neonatal stroke early enough in our differential dianosis?  Jouranl of Neonatal-Perinatal Medicine. 2014:7(4):293-299
2. Paddock M, Robson N. The curoius case of disappearing IVC: A case report and review of the aetiology of Inferior Vena Cava Agenesis. Journal of Radiology Case Reports. 2014;8(4):38-47.
3. Radiological Anatomy for FRCR Part 1. Borg P, Alvi AR, Skipper NT, Johns C. 2nd ed.Springer Berlin Heidelburg: 2014.

2012

1. Pulmonary artery relative area change detects mild elevations in pulmonary vascular resistance and predicts adverse outcome in pulmonary hypertension. Swift AJ, Rajaram S, Condliffe R, Capener D, Hurdman J, Elliot CA, Kiely DG, Wild JM, Invest Rad. 2012 Oct;47(10): 571-577
2. Diagnostic accuracy of cardiovascular magnetic resonance of right ventricular morphology and function in the assessment of suspected pulmonary hypertension. Swift AJ, Rajaram S, Condliffe R, Capener D, Hurdman J, Elliot CA, Wild JM, Kiely DG. J Cardiovasc Magn Reson. 2012 Jun 21;14(1)           
3. Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension. Swift AJ, Rajaram S, Marshall H, Condliffe R, Capener D, Hill C, Davies C, Hurdman J, Elliot CA, Wild JM, Kiely DG. Eur Radiol. 2012 Mar;22(3):695-702.
4. Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension. Rajaram S, Swift AJ, Capener D, Telfer A, Davies C, Hill C, Condliffe R, Elliot C, Hurdman J, Kiely DG, Wild JM. Eur Radiol. 2012 Feb;22(2):310-7.
5. Comparison of the diagnostic utility of cardiac magnetic resonance imaging, computed tomography and echocardiography in assessment of suspected pulmonary arterial hypertension in patients with connective tissue disease. Rajaram S, Swift AJ, Capener D, Elliot CA, Condliffe R, Davies C, Hill C, Hurdman J, Kidling R, Akil M, Wild JM, Kiely DG. J Rheumatol. 2012 Jun;39(6):1265-74.
6. Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT. Rajaram S, Swift AJ, Capener D, Telfer A, Davies C, Hill C, Condliffe R, Elliot C, Hurdman J, Kiely DG, Wild JM. Radiology 2012 May;263(2):569-77.
7. Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI. Marshall H, Deppe MH, Parra-Robles J, Hillis S, Billings CG, Rajaram S, Swift AJ, Miller SR, Watson JH, Wolber J, Lipson DA, Lawson R, Wild JM. Thorax. 2012 Jul;67(7):613-7.
8. CT and MRI findings in the basal ganglia in Non-Ketotic Hyperglycaemia Associated Hemichorea and Hemiballismus (HC-HB). Z Zaitout, DJA Connolly, K Karunasaagarar, R Batty. Neuroradiology. Volume 54, Number 10 (2012), 1119-1120.
9. 'Investigation of Paediatric Head Injury'. A Mathew, P Borg, R Jayarajasingam, T Win. Paediatric Radiology, Vol. 42 (Suppl 3) p.S534 (May 2012)

2011:

1. CT pulmonary angiography combined with echocardiography in suspected systemic sclerosis-associated pulmonary arterial hypertension. Condliffe R, Radon M, Hurdman J, Davies C, Hill C, Akil M, Guarasci F, Rajaram S, Swift AJ, Wragg Z, van Beek E, Elliot CA, Kiely DG. Rheumatology. 2011 Mar 29.

2010:

1. ‘Occlusion of the Profunda Femoris Artery in Competitive Cyclists’-Case-report. Mathew A, Fysh T, Bottomley JR, Thompson JF, Beard JD.European Journal of Vascular and Endovascular Surgery(Extra) March  2010. Volume 19, Issue 3, Pages e28-e30
2. Advances in epilepsy imaging. Craven I, Kotsarini C, Hoggard N.Postgraduate Medical Journal. (2010) 86:552-559
3. Radiological anatomy for FRCR part 1- Borg P, Alvi AR. 
   Springer; 1st Edition. (12 Oct 2010)

2016

1. Paddock M, Sprigg A, Offiah AC. 15-20 May 2016.  Imaging and reporting considerations for skeletal manifestations of inflicted injury in infants and young children: a pictorial review.  International Peadiatric Radiology (IPR) Congress, Chicago, USA.
2. Senasi R, Paddock M, Smith C, Wei XC, Raghavan A, Haider S.  A retrospective review of the techniques used for the diagnosis of H-type tracheoesophageal fistula across two paediatric regional centres. 12-14 September 2016. The Royal College of Radiologists Annual Scientifica Meeting (RCR ASM) 2016, London, UK (4-6 June 2015. 52nd Annual Meeting of the European Society of Paediatric Radiology (ESPR), Graz, Autrial).
3. Paddock M, Martin A, Lang I, Smith A.  Provisional reporting of Emergency Department radiographs and correlation with the final radioloical report. 12-14 September 2016. The Royal College of Radiologists Annual Society of Paediatric Radiology (RCR ASM)2016, London, UK (4-6 June 2015. 52nd Annual Meeting of the European Society of Paediatric Radiology (ESPR), Graz, Austria).
4.  Audit of nerve root blocks and associated documentation performed by neuroradiologists at Sheffield Teaching Hospitals. Rea B, Batty R, Connolly D, Skipper N. British Society of Neuroradiologists 2016 (York)

2015

1. Paddock M, Senasi R, Hare M, Ward R, Hough J, Raghavan A. 27 April - 1 May 2015.  Traumatic celiac artery disscection in an adolescent diagnosed using a computed tomography split bolus "Afghan" technique. Society of Paediatric Radiology (SPR) Annual Meeting 2015, Seattle, Wahington, USA.
2. 1H-MR spectroscopy as a diagnostic aid in MSA-C. Kadodwala V, Hadjivassilious M, Currie S, Skipper N, Larsen J, Connolly D, Batty R. American Society of Neuroradiology 2015 (Sheffield)

2012

1. Imaging pulmonary embolism in pregnancy: What is the value of routine bilateral leg Doppler ultrasound in women without symptoms of deep venous thrombosis?  Cooper M and Matthews S. European society of thoracic imaging congress. London; 2012
2. Orbital cellulitis: 10-year experience- A V Mathew, E Craig, R Al-Mahmoud, R Batty, A Raghavan, D Connolly. ESNR Conference, Edinburgh, September 2012
3. CT and MRI Findings in the Basal Ganglia in Non-Ketotic Hyperglycaemia Associated Hemi-chorea and Hemiballismus. Z Zaitout, T Julius, S Gagrani, K Karunasaagarar, DJA Connolly, R Batty.UKRC 2012.
4. Causes of increased T1W signal within the basal ganglia. Z Zaitout, S Gagrani, K Karunasaagarar, DJA Connolly, R Batty. American Society of Neuroradiology 50th Annual Meeting, New York 2012.
5. Lung cancer in 15 year old child presenting as pneumothorax with an incidental peripancreatic lymphangioma. Z Zaitout, T Julius, T Win.UKRC 2012.

2011

1. Clinical utility of MR pulmonary artery stiffness indices in unselected patients with pulmonary hypertension. Swift AJ, Rajaram S, Capener D, Marshall H, Hill C, Davies C, Hurdman J, Condliffe R, Elliot C, Wild JM, Kiely DG. RSNA 2011
2. Black blood MRI predicts early mortality in patients with suspected pulmonary hypertension. Swift AJ, Rajaram S, Marshall H, Condliffe R, Capener D, Hill C, Davies C, Hurdman J, Elliot C, Wild JM and Kiely DG.ESTI 2011
3. LV eccentricity Index strongly reflects mPAP in patients with IPAH using CINE cardiac MRI. Swift AJ, Rajaram S, Condliffe R, Marshall H, Capener D, Hurdman J, Elliot C, Kiely DG and Wild JM. ERS 2011
4. Cardiac MRI in connective tissue disease patients with suspected pulmonary hypertension: correlation between morphological and functional parameters and invasive measurements. Rajaram S, Swift AJ, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. EULAR 2011
5. Black blood MRI has high diagnostic accuracy in patients with suspected pulmonary hypertension. Swift AJ, Rajaram S, Capener D, Marshall H, Hill C, Davies C, Hurdman J, Condliffe R, Elliot C, Wild JM, Kiely DG. ATS 2011
6. MR LV Systolic Eccentricity Index Compared to Established Cardiac MR Parameters for the Diagnosis of PH: Correlation with Right Heart Catheterization. Swift AJ, Rajaram S, Capener, Condliffe R, Hurdman J, Elliot C, Wild JM and  Kiely DG. ATS 2011
7. Relative Area Change (RAC) Better Reflects Right Ventricular Ejection Fraction (RVEF) than Longitudinal or Transverse Functional Measurements in PH Patients. Swift AJ, Rajaram S, Capener D, Hurdman J, Condliffe R, Elliot C, Kiely DG, Wild JM. ISMRM 2011
8. 3D MR Pulmonary Perfusion in Connective Tissue Disease Patients: a non-invasive method of PVR estimation. Swift AJ, Rajaram S, Capener D, Hill C, Davies C, Condliffe R, Hurdman J, Elliot C, Wild JM, Kiely DG.EULAR 2011
9. 3D Time-resolved MR Perfusion in Patients with Chronic Thromboembolic Pulmonary Hypertension. Swift AJ, Telfer A , Marshall H, Rajaram S Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. National CTEPH meeting 2011
10. Novel Method for the Estimation of PCWP using CINE Cardiac MRI in Patients with Pulmonary Hypertension. Swift AJ, Rajaram S, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. ERS 2011
11. Diagnostic Accuracy of Contrast-Enhanced MRA and Non-Contrast Proton MRI Compared with CTPA in Chronic Thromboembolic Pulmonary Hypertension. Rajaram S, Swift AJ, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. ISMRM 2011
12. Assessment of lung morphology with steady state free precession (SSFP) MRI compared to computed tomography. Rajaram S, Swift AJ, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. UPenn 2011
13. Comparative study of SPSS lung MRI  with HRCT in patients with interstitial  lung fibrosis. Rajaram S, Swift AJ, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. ISMRM 2011
14. Effect of pulmonary fibrosis on pulmonary artery size in predicting pulmonary hypertension. Rajaram S, Swift AJ, Marshall H, Capener D, Condliffe R, Hurdman J, Elliot C, Kiely DG, Wild JM. ESTI 2011
15. Investigation of Paediatric Head Injury. A Mathew, P Borg, R Jayarajasingam, T Win. ESPR, Athens, June 2012
16. Audit of Appropriateness of Usage of CTPA in the Investigation of Suspected PE. Mathew A, Davies C. RCR Annual Scientific Meeting, September 2011
17. Evolving trends in AAA repair: Percutaneous Endovascular Aneurysm Repair. Mathew A, Alvi AJR, Kerr K, Bottomley J.  Vascular Anaesthetic Society ASM, September 2011
18. Selective Fully Percutaneous Endovascular Aneurysm Repair under Local anaesthetic (PEARLA): the Game-changer for Suitable Infra-renal Aortic Aneurysms. Bottomley J, Alvi AJR, Mathew A.  European Congress of Radiology, Vienna 2011 
19. MRI vs Endoscopy in Paediatric Inflammatory Bowel disease. Borg P, Win T. European Congress of Radiology 2011.

2010

1. The use of 3 Tesla MRI in epilepsy. - Craven I, Griffiths PD, Coley SC, Connolly D, Hodgson T, Romanowski CAJ, Batty R, Hoggard N. 
   British Society of Neuroradiologists. Glasgow 2010.  
2. Colonic stenting: Indications, technique and complications. - Kirwadi A, Chellamuthu S, Bansal M, Hampton J.RSNA 2010
3. Is Adrenal Vein Sampling Clinically Useful?: A Review of Local Experience. - Hersey N. BSIR Nov 2010

2009

1. The Plain Abdominal Radiograph-Often Used, Seldom Useful. Mathew A, Dubb A, Rehman A, Wolinski A. Gastro 2009 International Conference, London, November 2009
2. Extrinsic Causes of Gastric Outlet Obstruction: Diagnostic Imaging and Radiological-guided Stenting. Chellamuthu S, Hon L, Rathinavel B, Lee F. RSNA 2009.